SCIENCE: Speech and swallowing abnormalities in adults with POLG associated ataxia

• 100% of patients with POLG-A present with dysarthria and dysphagia

• POLG patients without ataxia do not present with speech or swallowing deficits.

• Speech is characterized by deficits in timing, voice quality and control.

• Swallowing function is effected by deficits of timing and coordination.

• Speech and swallowing deficits progress distinctly from other POLG-A dysfunctions like ataxia or cognitive impairment.

Click here for more details.

Tags: , , ,

Related Post

Perceptual and acoustic analysis of speech in spinocerebellar ataxia type 1

  • Posted on 10 March, 2023
    Speech is a cardinal and important feature of ataxia. We have put together a comprehensive description of dysarthria in spinocerebellar...
    Read more

    Characterization of dysphagia and longitudinal changes in swallowing function in adults with Niemann‑Pick disease type C treated with miglustat

    • Posted on 6 July, 2021
      Niemann-Pick disease type C (NPC) is a rare, autosomal recessive neurodegenerative disease, characterized by progressive psychiatric and neurological defcits. Neurological...
      Read more

      Instrumental swallowing assessment in adults in residential aged care homes: A scoping review

      • Posted on 14 December, 2020
        Objectives To systematically describe evidence on the use of instrumental swallowing assessment for residents of aged care homes. Design Scoping...
        Read more